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Carme Sole

Carme Sole


Profesor Lector en la Universitat Pompeu Fabra.


Máster en Neurociencia Experimental y Clínica

Universidad de Murcia

Síntesis curricular

Licenciada en Química i Bioquímica por la Universitat de Barcelona (2000).

Doctorada en Química por la Universitat de Lleida (2006).

Personal investigador Contrato Juan de la Cierva en la Universitat Pompeu Fabra (2007-2009).

Profesor Lector en laUniversitat Pompeu Fabra (2009-actualidad).


Casanelles E, Gozzelino R, Marqués-Fernández F, Iglesias-Guimarais V,
Garcia-Belinchón M, Sánchez-Osuna M, Solé C, Moubarak RS, Comella JX, Yuste VJ.
NF-?B activation fails to protect cells to TNF?-induced apoptosis in the absence
of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w. Biochim Biophys Acta. 2013

Solé C*, Nadal-Ribelles M*, Kraft C, Peter M, Posas F, de Nadal E. Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress. EMBO J. 2011 Jul 8;30(16):3274-84. (Co-authors, *) Moubarak RS*, Solé C*, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ,
Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM,
Soriano E, Yuste VJ, Comella JX. The death receptor antagonist FLIP-L interacts
with Trk and is necessary for neurite outgrowth induced by neurotrophins. J
Neurosci. 2010 Apr 28;30(17):6094-105. (Co-authors, *)

Klopf E, Paskova L, Solé C, Mas G, Petryshyn A, Posas F, Wintersberger U, Ammerer G, Schüller C. Cooperation between the INO80 complex and histone chaperones determines adaptation of stress gene transcription in the yeast Saccharomyces cerevisiae. Mol Cell Biol. 2009 Sep;29(18):4994-5007. Gozzelino R, Sole C, Llecha N, Segura MF, Moubarak RS, Iglesias-Guimarais V,
Perez-Garcia MJ, Reix S, Zhang J, Badiola N, Sanchis D, Rodriguez-Alvarez J,
Trullas R, Yuste VJ, Comella JX. BCL-XL regulates TNF-alpha-mediated cell death
independently of NF-kappaB, FLIP and IAPs. Cell Res. 2008 Oct;18(10):1020-36.
Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R,
Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E,
Yuste VJ, Comella JX. The long form of Fas apoptotic inhibitory molecule is
expressed specifically in neurons and protects them against death
receptor-triggered apoptosis. J Neurosci. 2007 Oct 17;27(42):11228-41.
Fernández M, Segura MF, Solé C, Colino A, Comella JX, Ceña V.
Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in
neurons via microdomain recruitment. J Neurochem. 2007 Oct;103(1):190-203. Epub
2007 Jul 17.
Moumen A, Ieraci A, Patané S, Solé C, Comella JX, Dono R, Maina F. Met signals
hepatocyte survival by preventing Fas-triggered FLIP degradation in a
PI3k-Akt-dependent manner. Hepatology. 2007 May;45(5):1210-7.
Yuste VJ*, Sánchez-López I*, Solé C*, Moubarak RS, Bayascas JR, Dolcet X, Encinas
M, Susin SA, Comella JX. The contribution of apoptosis-inducing factor,
caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear
phenotype and DNA degradation during apoptosis. J Biol Chem. 2005 Oct
21;280(42):35670-83. (Co-authors, *)
Solé C, Dolcet X, Segura MF, Gutierrez H, Diaz-Meco MT, Gozzelino R, Sanchis
D, Bayascas JR, Gallego C, Moscat J, Davies AM, Comella JX. The death receptor
antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and
NF-kapp B signaling. J Cell Biol. 2004 Nov 8;167(3):479-92.
Bayascas JR, Yuste VJ, Solé C, Sánchez-López I, Segura MF, Perera R, Comella
JX. Characterization of splice variants of human caspase-activated DNase with
CIDE-N structure and function. FEBS Lett. 2004 May 21;566(1-3):234-40.
Yuste VJ, Sánchez-López I, Solé C, Encinas M, Bayascas JR, Boix J, Comella
JX. The prevention of the staurosporine-induced apoptosis by Bcl-X(L), but not by
Bcl-2 or caspase inhibitors, allows the extensive differentiation of human
neuroblastoma cells. J Neurochem. 2002 Jan;80(1):126-39.